The Praxis General Science: Content Knowledge (5435) exam is a test required by many states for credential candidates planning to teach science at a high school level. It is a single, computer-delivered test that includes questions from five content domains.
The content categories are Scientific Methodology, Techniques, and History; Physical Science; Life Science; Earth and Space Science; and Science, Technology, and Society.
The test consists of selected-response questions only. Examinees will not need to use calculators. The periodic table of the elements is available as a Help screen, along with a table of information that presents various physical constants and several conversion factors among SI units.

2025 Praxis General Science Testing Costs*
Below is an overview of the 2025 Praxis General Science (5435) testing fees for computer-based testing.
Service |
Fees |
Registration |
$130 test registration fee |
Change to test center or date |
Additional $40 fee |
Phone Registration |
Additional $35 fee |
Additional score reports |
$50 per report |

2025 Praxis General Science Test Dates*
Computer-based testing for the Praxis General Science (5435) exam is available by appointment. Alternatively, online-proctored testing is offered remotely.
Praxis General Science Test Dates |
Results Release Dates |
6/30/25 - 7/26/25 |
8/8/25 |
8/4/25 - 8/30/25 |
9/12/25 |
9/2/25 - 9/27/25 |
10/10/25 |
10/6/25 - 11/1/25 |
11/14/25 |
11/3/25 - 11/22/25 |
12/5/25 |
12/1/25 - 12/27/25 |
1/9/26 |
12/29/25 - 1/31/26 |
2/13/26 |
2/2/26 - 2/21/26 |
3/6/26 |
3/2/26 - 3/28/26 |
4/10/26 |
3/30/26 - 4/25/26 |
5/8/26 |
5/4/26 - 5/30/26 |
6/12/26 |
6/1/26 - 6/27/26 |
7/10/26 |
6/29/26 - 7/25/26 |
8/7/26 |
8/3/26 - 8/29/26 |
9/11/26 |
*This information is subject to change. All test-takers should visit the official Praxis website at https://www.ets.org/praxis to confirm fees, registration, and testing requirements before enrolling.